If one in twenty does not seem high enough odds, we may, if we prefer it, draw the line at one in fifty (the 2 per cent. point), or one in a hundred (the 1 per cent. point). Personally, the writer prefers to set a low standard of significance at the 5 per cent. point, and ignore entirely all results which fail to reach this level. A scientific fact should be regarded as experimentally established only if a properly designed experiment rarely fails to give this level of significance.
Ronald FisherWe have usually no knowledge that any one factor will exert its effects independently of all others that can be varied, or that its effects are particularly simply related to variations in these other factors.
Ronald FisherThe best causes tend to attract to their support the worst arguments, which seems to be equally true in the intellectual and in the moral sense.
Ronald FisherWe can set no limit to human potentialities; all that is best in man can be bettered; it is not a question of producing a highly efficient machine, ... but of quickening all the distinctly human features, all that is best in man, all the different qualities, some obvious, some infinitely subtle, which we recognize as humanly excellent.
Ronald FisherAlthough no explanation can be expected to be satisfactory, it remains a possibility among others that Mendel was deceived by some assistant who knew too well what was expected. This possibility is supported by independent evidence that the data of most, if not all, of the experiments have been falsified so as to agree closely with Mendel's expectations.
Ronald Fisher