[With R-rated movie] you're not dealing with the restrictions imposed by the FCC. They're self-imposed. In a way, that does make it harder. You actually have to think about it, as opposed to just taking for granted that you're not going to be able to do this.

I'm not a fatalist. I'm not a religious person. I'm sure there are close calls that we're not even aware of hundreds of times a year. You cross the street, and if you'd crossed the street two minutes later, you'd have been hit by a car, but you'd never know it. I'm sure that kind of stuff happens all the time.

Evolution doesn't care whether you believe in it or not, no more than gravity does. I want to rekindle excitement over what we've achieved as a species with the space program. We can't afford to regress back to the days of superstition.

I hate people who say 'Just to play devil's advocate.'

I spent my entire childhood in the same town, in Kent. I went to grade school there. There was a boarding school that my mother taught at, called - appropriately enough - Kent School, that I went to. Yeah, pretty much my entire childhood was spent in that town.

There are people on staff who have made that point, that the upside to a second Bush term is that it makes 'American Dad' work better. To me, the price is too high. I would gladly give up the comedy to have a President Kerry. But you work with what you have.

The worst thing to happen at the Oscars would be if nothing happened. You want something unscripted, something to riff on, something kinda out there.