I think around that time I met David [Gordon Green] or, well, we all met at Superbad and Judd [Apatow] said, 'I'm thinking about having him direct [ Knocked Up].' Sounded like a good idea.

Honestly, it's really hard improvising and it's really stressful and humiliating at times. You're taking really big swings that potentially are eating up a lot of people's time and resources at set in your attempt to discover something funny.

Shutting people down creatively often doesn't get the best performance out of them.

There's something you can get away with when you know you're only going to be on one season. There's no sense of, "We should save that." It's just like, "Use that! Get it out there now. They could shut us down any second!"

In my sick brain, gruesome violence and comedy go as hand-to-hand together as anything else in the world.

A TV show is constant work, which is the great thing about it.

I don't smoke weed on set all day. I just want to say that, you know, not all day. After lunch you get tired. What can you do? To me, the fact that a character smokes weed isn't really what I hang my hat on necessarily.