I don't pretend there aren't biological differences, but I don't believe the desire for leadership is hardwired biology, not the desire to win or excel. I believe that it's socialization, that we're socializing our daughters to nurture and our boys to lead.

The reason I wrote Lean In is I think people weren't actually noticing that we had stopped making progress. I gave a TED talk and said: "It turns out men still run the world." And the audience gasped as if that was news.

Facebook is great for women and men. We are enormously flexible. We care a lot about great opportunities for women, we push ourselves to make things as flexible as possible.

The traditional metaphor for careers is a ladder, but I no longer think that metaphor holds. It just doesn’t make sense in a less hierarchical world... Build your skills, not your resume. Evaluate what you can do, not the title they’re going to give you. Do real work. Take a sales quota, a line role, an ops job. Don’t plan too much, and don’t expect a direct climb. If I had mapped out my career when I was sitting where you are, I would have missed my career.

I don't hold myself out as a role model. I don't believe that everyone should make the same choices; that everyone has to want to be a CEO, or everyone should want to be a work-at-home mother. I want everyone to be able to choose. But I want us to be able to choose unencumbered by gender choosing for us.

The most important thing we're doing differently is that we talk openly about gender at Facebook.

Every job will demand some sacrifice. The key is to avoid unnecessary sacrifice.