Dreams are lovely. But they are just dreams. Fleeting, ephemeral, pretty. But dreams do not come true just because you dream them. It's hard work that makes things happen. It's hard work that creates change.

It can be scary to find out you've been wrong about something but we can't be afraid to change our minds, to accept that things are different, that they'll never be the same, for better or for worse. We have to be willing to give up what we used to believe. The more we're willing to accept what is and not what we thought, we'll find ourselves exactly where we belong.

I want my daughters to see me and know me as a woman who works. I want that example set for them... I am a better mother for it. The woman I am because I get to run Shondaland, because I get write all day, because I get to spend my days making things up, that woman is a better person - and a better mother. Because that woman is happy. That woman is fulfilled. That woman is whole. I wouldn't want them to know the me who didn't get to do this all day long. I wouldn't want them to know the me who wasn't doing.

You can waste your lives drawing lines. Or you can live your life crossing them.

I don't understand why people don't understand that the world of TV should look like the world outside of TV.

Finally I want to say this: If you are a kid and you are out there and you are chubby and not so cute and nerdy and shy and invisible and in pain, whatever your race, whatever your gender, whatever your sexual orientation, I’m standing here to tell you: You are not alone. Your tribe of people, they are out there in the world. Waiting for you.

Nobody got anything great by playing it safe.