It was like in the film, when I was actually doing a take and wasn't quite sure of the context, and then in the completed film it works beautifully.In the end I didn't know why I felt so shitty doing it, and why it turns out great in the final product. I guess you have to live in that unknown.

I came in ["MADtv"] kind of late in the season. Some of the producers didn't want me but the network did. It was all (messed up) from the beginning.

I was young. I was 23 or 24. I just wasn't a fan of the politics of campaigning - of going into that environment and competing and trying to get into the good graces of the writers.

I wanted to move on. I wanted to do acting. The next thing I did after [MADtv] was a good hybrid of that. I did this show with Bob Odenkirk and Derek Waters (creator of Comedy Central's "Drunk History") and it was a little homegrown thing that we shot and then we sold it to HBO. We made a pilot and HBO didn't pick it up, but then we made all these webisodes. This was before streaming stuff online made any sense. (The episodes are available on YouTube). Nobody even knew how to watch things on the internet.

It was like in the film, when I was actually doing a take and wasn't quite sure of the context, and then in the completed film it works beautifully.In the end I didn't know why I felt so shitty doing it, and why it turns out great in the final product. I guess you have to live in that unknown.

The weird part is actually, there were so many exceptionally talented people there [ on "MADtv"]. But it was a disaster. I don't think I enjoyed any of it, really. I had a different sensibility.

When you have this long of a run [in The Big Bang Theory], you don't have to have something happen every episode. Like, Sheldon lost his virginity last season and in the first season he didn't even like girls. So I feel like you can earn that stuff. And that is really fun, because you get to find new layers. It's a testament to the writing.