Certainly there was the Affordable Care Act part, then unaccompanied children [there has been a surge of children entering the country illegally and without parents, particularly in Texas], and things like, we find smallpox in an NIH lab, after 50 years? Why didn't you find it, like, five weeks ago or three years ago? There was thing after thing. But the big ones were [dealing with] the Ebola [outbreak], the unaccompanied children. [It was] perhaps a bigger challenge than I had calculated on my yellow pad as I was thinking about this role.

Across the globe, regardless of nationality or financial status, there is a common dream every mother has for her children - for them to live full, healthy and productive lives. As a mother, I share that dream for my children.

I have been fortunate to work in places where people have a passion for their work. At HHS the passion sort of exceeds passion - it's a vocation.... I obviously knew that there were certainly some challenges that I would be taking on both with the work and the politics. [But] I probably did not have the right expectation level with regard to the number and volume of crises that would occur.

We know there are states, like Alaska, where there are not a lot of providers. How do we work on issues like that? How do we work on making sure that the small-business part of this works better?... And if people have [alternate] plans, let's compare them and see. Access, affordability, and quality - that's what this is about. [But] "repeal" is a symbol of something that I don't think is connected to the substance of what's happening. Do you want to take away care from people who have preexisting conditions? [Repeal] takes you backward.

Technologies, including cell phones, have the potential to help millions of poor people out of poverty by enabling access to a range of safe, affordable financial services - most importantly, savings accounts - that have long been out of reach.

So we want to make it easier to shop and understand products because many people aren't educated about what's offered - do you know your premiums? Do you know your copays? Do you know your deductibles? And so figuring out ways that we help people understand what this is, how it works, and that they can shop to get what they need.

As a global community, we must ensure that legitimate concerns about liability do not hold back the possibility of developing an Ebola vaccine, an essential strategy in our global response to the Ebola epidemic in West Africa.