The sceptics end in the infidelity which asserts the problem to be insoluble, or in the atheism which denies the existence of any orderly progress and governance of things: the men of genius propound solutions which grow into systems of Theology or of Philosophy, or veiled in musical language which suggests more than it asserts, take the shape of the Poetry of an epoch.
Thomas HuxleyAny one who has studied the history of science knows that almost every great step therein has been made by the "anticipation of Nature," that is, by the invention of hypotheses, which, though verifiable, often had very little foundation to start with; and, not unfrequently, in spite of a long career of usefulness, turned out to be wholly erroneous in the long run.
Thomas Huxley