It is predicated on the assumption that you dislike what you are doing during the most physically capable years of your life. This is a nonstarter—nothing can justify that sacrifice.

The only rules and limits are those we set for ourselves

It's not enough to have the right answers. You have to have the right questions.

Poisonous people do not deserve your time. To think otherwise is masochistic.

The downstream effects are unknown. Do your best and hope for the best. If you're improving the world-however you define that-consider your job well done.

There is always more information than attention

Effectiveness is doing the things that get you closer to your goals. Efficiency is performing a given task (whether important or not) in the most economical manner possible. Being efficient without regard to effectiveness is the default mode of the universe.