I feel a lot of personal responsibility to undo the negative stereotypes. I know that it's not coming from a bad place. It's coming from an ignorant place. I can sort of be an ambassador in a subtle way to say, "This is what I am: a comedian, a show host, a writer." It will still always be part of the conversation and people will want to focus on it because there is a culture that is so embedded that if you have a disability, you're someone to be either admired just for living, or be pitied for having to struggle.

The waiter just flashed me something that said, "Chew bubblegum." Every morning, when I was about to go to the Oprah competition, my friend used to say this line in a video game to me: "It's time to kick ass and chew bubble gum." There's a strict policy that you can't encourage anyone on a reality show, that would give them an edge.

When I got my Oprah money, the first thing I bought was a really nice electronic bidet toilet seat. It just feels like this is what we should be doing. For everybody who uses it, it's like there's no goin' back.

I had to write a comedy set and film a show at the same time. And it's the second time I've been up on stage as a stand-up comedian with untested material. I was saying it out loud for the first time that night. It didn't go how I expected, but in the best possible way.

You can never walk a mile in someone elses shoes, but you can walk a mile in your own and be proud of it.

When I read the script [of Glee], the whole premise was that all the high school kids were being cruel to this kid in the wheelchair, and then the quarterback comes along and has a heart of gold and takes him out of a Porta Potty. That's too often what I see in media, that the characters with disabilities are there to make other people seem like heroes for treating the character with a disability with respect. Those are the kinds of roles that are out there.

I talk about Breaking Bad being the most brilliant show ever, and even minor characters have subtle nuances and are fully drawn.