Everyone who was here [Sheraton Universal Hotel] when I won still works here, so the two biggest moments in my career are intersecting. It's so cool that I can say "hi" to everybody.

I feel a lot of personal responsibility to undo the negative stereotypes. I know that it's not coming from a bad place. It's coming from an ignorant place. I can sort of be an ambassador in a subtle way to say, "This is what I am: a comedian, a show host, a writer." It will still always be part of the conversation and people will want to focus on it because there is a culture that is so embedded that if you have a disability, you're someone to be either admired just for living, or be pitied for having to struggle.

There's a whole chapter about my unfortunate manscaping accident. I was so focused on, "I've got to look this certain way and do this to be ready for this." So I missed out on a lot.

When I got my Oprah money, the first thing I bought was a really nice electronic bidet toilet seat. It just feels like this is what we should be doing. For everybody who uses it, it's like there's no goin' back.

I didn't feel like I was putting anything good into the world, even though it was funny. I wanted to do something more positive that would have an impact. So even when I'm doing naked push-ups or whatever, it's astounding to see how people respond to it.

Nothing like quoting Silence of the Lambs for people to question what kind of disability you have.

I've come to be pretty selective about the type of advocacy that I do, because I kind of feel like it's stronger to just do my work and let it speak for itself.