I believe innovation is the most powerful force for change in the world. People who are pessimistic about the future tend to extrapolate from the present in a straight line. But innovation fundamentally shifts the trajectory of development.

Nobody has a guaranteed position in computer technologies business. We've done some good work, but all of these products become obsolete so fast and the structure of the business as it broadens out is going to be so different.

Vaccines are a miracle; they're fantastic. Anything that makes people hesitate to give their children these vaccines according to the recommended schedule creates risk. Risk for the children who don't get vaccinated and risk for children, some of whom don't have an immune system, so they're benefiting from the fact that the community protection means the disease doesn't get to them.

We are seeing smarter philanthropy, more philanthropy, and that's true world wide. So it's kind of a movement that has a lot of accomplishments, even though as a percentage of the economy, it's still only a few per cent.

Life is not a continuous process, there's some sort of finite number of achievements that defines your life.

For all these infectious diseases, the goal is to eventually get rid of them. And to do that we need to invent new tools, but nobody was doing that because there was no money to buy on behalf of the poorest, even the existing tools.

Some people, through luck and skill, end up with a lot of assets. If you're good at kicking a ball, writing software, investing in stocks, it pays extremely well.