Take crack cocaine. Particularly in the early days of the policy, ninety percent of the people being arrested were black, even though they didn't use the drug at higher rates and even though their numbers in the general population are so low. How could that be? The thing is, you place all your resources in communities of color. And if you do that, you're going to arrest black people.

Writing in a nuanced way, getting at all the details in a way that remains interesting for the reader, is very difficult.

Much of the early work focused on dopamine and we were really looking for rewarding sorts of effects and sure enough, we only found that. But you can destroy the main dopamine-producing structures of the brain and you can still get an animal to self-administer drugs like cocaine.

Looking at the data and at my drug use and evaluating it carefully just let me see that I wasn't special, but my drug use challenged what I thought about cocaine. Because I would accept when I would say, "What happened to that person?" and someone would say, "They started using cocaine...they went downhill..." I would just accept that, even though I had a different experience and all these other people had a different experience. But I would throw that out because I thought my experience was an aberration.

Take crack cocaine. Particularly in the early days of the policy, ninety percent of the people being arrested were black, even though they didn't use the drug at higher rates and even though their numbers in the general population are so low. How could that be? The thing is, you place all your resources in communities of color. And if you do that, you're going to arrest black people.

If you're a member of a despised group, look out! They'll find a drug and associate you with its use. There are a lot of people in the gay community using methamphetamine and paying taxes and going to work and doing well.

One of the things that has happened is that our drug laws have been institutionalized now. If you want to say that somebody's a bad person in a movie or in a television show or something about that, you say they sell drugs or they use drugs.