The brain seems a thoroughfare for nerve-action passing its way to the motor animal. It has been remarked that Life's aim is an act not a thought. To-day the dictum must be modified to admit that, often, to refrain from an act is no less an act than to commit one, because inhibition is coequally with excitation a nervous activity.

The terminal path may, to distinguish it from internuncial common paths, be called the final common path. The motor nerve to a muscle is a collection of such final common paths.

If it is mind that we are searching the brain, then we are supposing the brain to be much more than a telephone-exchange. We are supposing it to be a telephone-exchange along with subscribers as well.

If we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.

Swiftly the head mass becomes an enchanted loom where millions of flashing shuttles weave a dissolving pattern, always a meaningful pattern though never an abiding one...

He solved at a stroke the great question of the direction of nerve-currents in their travel through brain and spinal cord.

The brain is a mystery; it has been and still will be. How does the brain produce thoughts? That is the central question and we have still no answer to it.