He solved at a stroke the great question of the direction of nerve-currents in their travel through brain and spinal cord.
Charles Scott SherringtonThat our being should consist of two fundamental elements [physical and psychical] offers I suppose no greater inherent improbability than that it should rest on one only.
Charles Scott SherringtonAs followers of natural science we know nothing of any relation between thoughts and the brain, except as a gross correlation in time and space.
Charles Scott SherringtonThe brain seems a thoroughfare for nerve-action passing its way to the motor animal. It has been remarked that Life's aim is an act not a thought. To-day the dictum must be modified to admit that, often, to refrain from an act is no less an act than to commit one, because inhibition is coequally with excitation a nervous activity.
Charles Scott SherringtonNatural knowledge has not forgone emotion. It has simply taken for itself new ground of emotion, under impulsion from and in sacrifice to that one of its 'values', Truth.
Charles Scott SherringtonIf we denote excitation as an end-effect by the sign plus (+), and inhibition as end-effect by the sign minus (-), such a reflex as the scratch-reflex can be termed a reflex of double-sign, for it develops excitatory end-effect and then inhibitory end-effect even during the duration of the exciting stimulus.
Charles Scott Sherrington