To me, it's not about being anywhere, but being able to change my perceptions and experience something new.

Our role is to develop techniques that allow us to provide emergency life-saving procedures to injured patients in an extreme, remote environment without the presence of a physician.

Most budget airlines anywhere in the world are going to leave you dissatisfied after using them.

You can't just ignore spacewalking suit; it partially defines the experience. So maybe the most difficult thing is becoming completely attuned to efficiently wearing a garment that is so inhibiting to motion, and making it look effortless, as if it's the most natural thing to be out there on a spacewalk.

Imbibe three or four times as much water as you think you need and skip at least one, if not two meals, when you are travelling. You should arrive at your destination feeling slightly hungry and your digestive system reset.

The cool things about space is when you put your pants on here, you can put them on two legs at a time.

My optimism and confidence come not from feeling I'm luckier than other mortals, and they sure don't come from visualizing victory. They're the result of a lifetime spent visualizing defeat and figuring out how to prevent it. Like most astronauts, I'm pretty sure that I can deal with what life throws at me because I've thought about what to do if things go wrong, as well as right. That's the power of negative thinking.