If you start thinking that only your biggest and shiniest moments count, you're setting yourself up to feel like a failure most of the time.

My optimism and confidence come not from feeling I'm luckier than other mortals, and they sure don't come from visualizing victory. They're the result of a lifetime spent visualizing defeat and figuring out how to prevent it. Like most astronauts, I'm pretty sure that I can deal with what life throws at me because I've thought about what to do if things go wrong, as well as right. That's the power of negative thinking.

The Nile, draining out into the Mediterranean. The bright lights of Cairo announce the opening of the north-flowing river’s delta, with Jerusalem’s answering high beams to the northeast. This 4,258 mile braid of human life, first navigated end-to-end in 2004, is visible in a single glance from space.

As I have discovered again and again, things are never as bad (or as good) as they seem at the time.

It is spectacular. From about five minutes in, when we knew for sure that we were going to have the weather to go, the smile on my face just got bigger and bigger, and I was just beaming through the whole launch. I mean, it is just an amazing ride.

In any new situation, whether it involves an elevator or a rocket ship, you will almost certainly be viewed in one of three ways. As a minus one: actively harmful, someone who creates problems. Or as a zero: your impact is neutral and doesn't tip the balance one way or the other. Or you'll be seen as a plus one: someone who actively adds value. Everyone wants to be a plus one, of course. But proclaiming your plus-oneness at the outset almost guarantees you'll be perceived as a minus one, regardless of the skills you bring to the table or how you actually perform.

Scientific literacy is one of the underpinnings of everything I do. It's why I work with schools. It's why I teach at university. I do a lot of outreach to try and improve general scientific literacy, but the core of all scientific literacy is just literacy.