If you want to create something great and do it faster than the competition, you need to be action oriented.

If you have an idea that you can't get out of your head, do a startup. Otherwise join a startup.

Early in a startup, product decisions should be hunch driven. Later on, product decisions should be data driven.

Money is information, like bits.

Marketing is for companies who have sucky products.

We need new medical approaches to preventing and/or curing disease. We need new scientific approaches to generating, storing, and being more efficient with energy. Maybe we need more space exploration. Maybe we need more undersea exploration.

Foursquare's adoption of a game dynamic when it launched is a particularly clever implementation of a social hook.