I always wanted to be a scientist. I don't really have any writer friends. The process of being a writer is much more interior than being a scientist, because science is so reactionary. I think that all research scientists think of themselves as belonging to a grand tradition, building on work that has been worked on since the very beginning of science itself. Whereas I'm not sure writers think of themselves in the same way.

To be a scientist you have to be willing to live with uncertainty for a long time. Research scientists begin with a question and they take a decade or two to find an answer. Then the answer they get may not even answer the question they thought it would. You have to have a supple enough mind to be open to the possibility that the answer sometimes precedes the question itself.

I'm not sure a person ever really reveals the whole of himsels or herself to another person, and I'm not sure we should. Or rather, just because you don't, it doesn't mean you can't have a meaningful relationship with another person. It's important to remember that this idea of confessing your most shameful, embarrassing stories and self to someone else as an expression of love and intimacy is a relatively recent phenomenon, and a new definition of what it means to be close to someone. After all, the self is by its nature secretive.

It is always sort of unnerving to hear from people who've read my books. I'm not reading any of the reviews and most of my friends haven't read it - they bought it, which is all I frankly care about, but they haven't read it.

I'm an indulgent writer - I'm not sure, however, that's something I'm interested in changing. Writing should be indulgent: you should take big risks on the page, you should make big mistakes, you should be excessive at times. I let myself do as a writer what I probably would be less likely to allow as an editor.

I have one friend to whom I've told more than I've ever told anyone, and yet there are significant territories I have and will never let him access - in large part because I'm trying to protect him, and one of the responsibilities of loving someone is protecting him or her, even if who you're protecting them from is yourself.

We're living in a literary age, at least in America, that is marked by a sense of distance, a coolness, in all senses of that word. To be too obviously, unapologetically emotional is to risk being considered foolish, or at the very least not serious.