Sometimes the most difficult thing you can do as an editor is not make a single note - the idea that everything and everyone needs editing is, in reality, a fiction. I've gotten pieces where I thought, Well, I could do this or that, or change this word, but in the end, I leave it. Changing something is not necessarily equivalent to making the piece more true to itself, which is the point of editing: it's just changing it because you feel you can or should or must.

The big characters who occupy science, especially modern science, are all "off" in fundamental ways. I don't think that genius goes hand in hand with being socially inept or being a sociopath or being a misanthrope, but I do think that it is a mind that can think so differently - so beyond how one is supposed to think. I wanted to pay tribute to that mind.

There are times I wish I didn't have a job, even though I love my job: I get to work with interesting, eccentric colleagues and equally interesting and eccentric subject matter, both of which are rarities. But, naturally, I would treasure having more freedom someday: of time and of movement. Will I always have a full-time job? I don't know. But I do know that I need to spend at least part of my week in an office, with other people.

When you're 21 you think, "Old people sound like this. Old people think like this." I don't think my ideas about aging and about eternal life changed that much, but it became more poignant to me as I did get older and I could better imagine, as you sort of inch closer to death every day, why legacy, more than aging, becomes important to people.

I credit my parents for many things that had never seemed remarkable when I was growing up, and one of those things is how nonthreatened they were by my constant search for backup parents - other mothers and fathers would have bristled at this, but they never did. So I was always looking for other parental stand-ins, and I always found them.

When you never leave the literary biosphere, you forget how few people actually read books, and that in turn makes you start overestimating both your ability to make money and your relative renown, which has dangerous consequences: the first means you may end up in debt; the second means you may end up a horrid bore.

There are some writers who also enjoy being authors, and are good at it as well. There is nothing performative about writing, but there is about being a writer.