You always have to know what the ambition of the scene is, what the purpose of that scene is in the telling of the story overall, so that you're there to support the story.

It doesn't matter to me whether I go back to outer space or not [while acting]. The job's the same and I don't have any sort of genre preferences. I'm looking for a good story and a good character, whether earthbound or not.

Henry: Well I'm sorry about your head though, but I thought you were one of them. Indiana: Dad, they come in through the doors.

The trick of this thing and the beauty of this thing is that it's a cowboy movie first and then stuff happens. Even after stuff happens it doesn't change - it hasn't suddenly changed into another kind of movie. It's still a cowboy movie. And that's what's incredible about it because nobody has done that before, that's new territory.

I thought it was funny. I always thought Star Wars and Indiana Jones were basically comedies. The humour came out of their relationships; it came out of the fact that we were basically types.

Never again will I allow our political self-interest to deter us from doing what we know to be morally right. Atrocity and terror are not political weapons. And to those who would use them, your day is over. We will never negotiate. We will no longer tolerate and we will no longer be afraid. It's your turn to be afraid.

Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].