Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

I rarely play a real person, because I don't think I'm a good imitator.

What I think is important for a young person is to figure out how to be useful and not be so concentrated on themselves, but to see what they can do to make the overall collaboration with all the other people involved in a movie work better.

I don't think I have something that's pronounceable as a philosophy. ... When it was fashionable to say, "May the Force be with you," I always said, "Force yourself." ... I'll say again then, "The Force is within you. Force yourself."

There is no barrier to Indiana Jones growing older. It's not an age-based character. We can't bang him up as much as we used to, maybe. But I guess I can pretend to have the capacity as well as I pretended before.

It doesn't matter to me whether I go back to outer space or not [while acting]. The job's the same and I don't have any sort of genre preferences. I'm looking for a good story and a good character, whether earthbound or not.

I am not the first man who wanted to make changes in his life at 60 and I won't be the last. It is just that others can do it with anonymity.