Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

It's not the years honey, it's the mileage.

Whoever had the bright idea of putting Indiana Jones in a leather jacket and a fedora in the jungle ought to be dragged into the street and shot.

What is news? It's hard to quantify. Certainly news has changed completely, and the morning shows are not really designed to bring you the news, except to tell you what happened overnight, and the rest of it is a kind of magazine mentality - a little bit of this, a little bit of that. It's harder to be an educated and informed citizen.

My older kids are fantastic people. It can't be the result of my influence on them.

When I first started out, I was a bad actor.

The trick of this thing and the beauty of this thing is that it's a cowboy movie first and then stuff happens. Even after stuff happens it doesn't change - it hasn't suddenly changed into another kind of movie. It's still a cowboy movie. And that's what's incredible about it because nobody has done that before, that's new territory.