Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

I didn't play much ball. I wasn't much of a ball fan.

Acting was a way out at first. A way out of not knowing what to do, a way of focusing ambitions. And the ambition wasn't for fame. The ambition was to do an interesting job.

Never again will I allow our political self-interest to deter us from doing what we know to be morally right. Atrocity and terror are not political weapons. And to those who would use them, your day is over. We will never negotiate. We will no longer tolerate and we will no longer be afraid. It's your turn to be afraid.

My work has always been important to me. The reason I continue to do it is because it's so much fun for me. I love my work and so that's what keeps me in the game.

I rarely play a real person, because I don't think I'm a good imitator.

The loss of anonymity is something that nobody can prepare you for. When it happened, I recognized that I'd lost one of the most valuable things in life. To this day, I'm not all that happy about it