Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

I think you have to be very careful with effects that they don't overpower the story with the visual element.

Really, what are the options? Levi's or Wranglers. And you just pick one. It's one of those life choices.

What I hate is the loss of anonymity.

I'm ambitious for is to not get caught 'acting'. I want to really feel the role and not let people see the process, or to let them stand back and admire it, because I think that does finally get in the way.

I have the ordinary experience of being anonymous when I'm in an airplane talking to air-traffic control, and they don't know who they're talking to. I have a lot of common experiences.

There is no child left within me, none whatsoever.