Because the character is a fiction, he's a composite of other contributors to the science that brought this enzyme therapy through the process. We had the opportunity to make him up out of those things that helped tell the story. We wanted to create both ally and antagonist for John [in the Extraordinary measures].

I rarely play a real person, because I don't think I'm a good imitator.

The only thing that I have done that is not mitigated by luck, diminished by good fortune, is that I persisted, and other people gave up.

It doesn't matter to me whether I go back to outer space or not [while acting]. The job's the same and I don't have any sort of genre preferences. I'm looking for a good story and a good character, whether earthbound or not.

I didn't play much ball. I wasn't much of a ball fan.

I never feel sexy. I have a distant relationship with the mirror.

It's a wonderful opportunity to be part of a child's growing up, which is always an endless springtime. You see the blossoming and the growing and the nurturing and the payoff.