I think good-looking people seldom make good television. And American television studios almost concede before they start: 'Well, it won't be good, but at least it'll be good-looking. We'll have nice-looking girls in tight shirts with F.B.I. badges and fit-looking guys with lots of hair gel vaulting over things.'

Driving a motorcycle is like flying. All your senses are alive.

I grew up with an impatience with the anti-scientific. So I'm a bit miffed with our current love affair with all things Eastern. If I sneeze on the set, 40 people hand me echinacea. But I'd no sooner take that than eat a pencil. Maybe that's why I took up boxing. It's my response to men in white pajamas feeling each other's chi.

Driving a motorcycle is like flying. All your senses are alive. Being House is like flying, too. He's free of the gravity of what people think.

To be able to pretend to be something that I'm frankly not is very liberating and exciting.

I have been instrumental in banning bottled water on the set. It hasn't gone that well with the crew... so I replaced it with tequila.

Happiness is the twinkle in your grandmother's eye as you reverse the tractor off her legs.