Suffering is always hard to quantify - especially when the pain is caused by as cruel a disease as Alzheimer's. Most illnesses attack the body; Alzheimer's destroys the mind - and in the process, annihilates the very self.

A fishnet is made up of a lot more holes than strings, but you can't therefore argue that the net doesn't exist. Just ask the fish.

It's one of the worst-kept secrets of family life that all parents have a preferred son or daughter, and the rules for acknowledging it are the same everywhere: The favored kids recognize their status and keep quiet about it - the better to preserve the good thing they've got going and to keep their siblings off their back.

Narcissism, like the other personality disorders, is a condition that's known as ego-syntonic. In other words, the paranoid person really does believe that people are after him, and the narcissist really does believe that he or she is better than or more entitled than other people, and truly doesn't see why that's not the case.

Spare a thought for the poor introverts among us. In a world of party animals and glad-handers, they're the ones who stand by the punch bowl. In a world of mixers and pub crawls, they prefer to stay home with a book. Everywhere around them, cell phones ring and e-mails chime and they just want a little quiet.

The vexing thing about human behavior is that when we say we know we should do something, we really and truly do know it. It's hard to be 50 lbs. overweight or smoke a pack a day or feel miserable every moment you spend at work and not understand in a deep and primal way that change is in order - and that in some cases it could even save your life.

Sisters have ways of socializing brothers into the mysteries of girls. Brothers have ways of socializing sisters into the puzzle that is boys.