Most brain scientists have not taught 4th grade, and don't know very much about the classroom, even though they might study learning in some detail. Most education professionals, who often know a tremendous amount about the classroom, don't know much about the brain. That is one of the reasons why I am so skeptical about applying brain findings to the classroom.

There is a neuron in your brain that will respond only to pictures of Jennifer Aniston - provided you have had prior visual exposure to the actress. That neuron does not respond to pictures of Bill Clinton or Halle Berry. Only Jennifer. I used the story to explain the almost ridiculous plasticity of the organ. There is no such thing as Jennifer Aniston in our evolutionary history - she was born in 1969, for heaven's sake - but we are flexible enough to devote an entire cell to her if we have previously encountered her in some fashion.

Our ability to adapt came from our East African birthplace, a meteorologically unstable place. If you couldn't adapt, you'd be dead. But once you've found a solution, there is no need to continue the adaptive behavioral parrying, which is bioenergetically very expensive to maintain. We are built to find answers, then hang on to them as long as we can.

Americans have been good at improvising for a long time, but in the last few decades, we have gotten very sloppy about the rote memorization of facts. That's a discipline issue. You need the rote skill in order to have something to improvise off of, otherwise you are simply playing air guitar.

Babies learn through a series of increasingly self-corrected ideas. They use very sophisticated hypothesis testing strategies to find out about their world.

Human learning is a very aggressive style in its native state. I am not sure why, though it is a very useful trait in an unstable, unpredictable living environment.

What you do and learn in life physically changes what your brain looks like—it literally rewires it.