To ensure continuing prosperity in the global economy, nothing is more important than the development and application of knowledge and skills.

To most people in the UK, indeed throughout Western Europe, space exploration is primarily perceived as 'what NASA does'. This perception is - in many respects - a valid one. Superpower rivalry during the Cold War ramped up US and Soviet space efforts to a scale that Western Europe had no motive to match.

In our interconnected world, novel technology could empower just one fanatic, or some weirdo with a mindset of those who now design computer viruses, to trigger some kind of disaster. Indeed, catastrophe could arise simply from technical misadventure - error rather than terror.

In the case of climate change, the threat is long-term and diffuse and requires broad international action for the benefit of people decades in the future. And in politics, the urgent always trumps the important, and that is what makes it a very difficult and challenging issue.

The 'clean energy' challenge deserves a commitment akin to the Manhattan project or the Apollo moon landing.

Once the threshold is crossed when there is a self-sustaining level of life in space, then life's long-range future will be secure irrespective of any of the risks on Earth. Will this happen before our technological civilization disintegrates, leaving this as a might-have-been? Will the self-sustaining space communities be established before a catastrophe sets back the prospect of any such enterprise, perhaps foreclosing it forever? We live at what could be a defining moment for the cosmos.

Devastation could arise insidiously, rather than suddenly, through unsustainable pressure on energy supplies, food, water and other natural resources. Indeed, these pressures are the prime 'threats without enemies' that confront us.