You know boys, a nuclear reactor is a lot like women. You just have to read the manual and press the right button.

'The Simpsons' from the very beginning was based on our memories of brash '60s sitcoms - you had a main title theme that was bombastic and grabbed your attention - and when you look at TV shows of the 1970s and '80s, things got very mild and toned down and... obsequious.

It's just hard not to listen to TV: it's spent so much more time raising us than parents have.

The French are funny, sex is funny, and comedies are funny, yet no French sex comedies are funny.

Cartooning is for people who can't quite draw and can't quite write. You combine the two half-talents and come up with a career.

I thought I had an appetite for destruction, but all I wanted was a club sandwich.

Basically, everything I try to do is to present an alternative to what somebody else is doing.