I went to business school, and I went straight from that to a nine-year career at Microsoft. Eventually, I ran a big chunk of the consumer products division for Microsoft.Then I left with the birth of our first daughter because Bill and I both wanted to have a few kids.

We look in our own backyard and say, 'How do we help at-risk families, at risk youth? How do we think through some of the problems affecting the Pacific Northwest and make some change there?'

We started our foundation because we believe we have a real opportunity to help advance equity around the world, to help make sure that, no matter where a person is born, he or she has the chance to live a healthy, productive life.

When girls are educated and free to pursue their passions, they contribute more to a thriving society. When women have a voice, they raise it to demand a life that is greater than what they've been told they have a right to expect. And these demands change the future for everyone.

We also look at farming. Are we making sure that we're getting the latest seeds out to women so they can get a bigger yield off of their farms? A new type of seed that gets out to a man, let's say, that's drought resistant - because, of course, the rains are changing in Africa with climate change - if you don't put it in the hands of a woman, she won't necessarily get it. We look at breaking down all those barriers.

The biggest killers of children around the world are two things: diarrhea and pneumonia. When you think about it, in the United States, kids don't die of diarrhea anymore, but it's a huge problem in the developing world.

All of a sudden people in the United States start to realize that vaccines make a difference. The controversy and the myth that's there, we're always trying to bust through that. So when I see a disease outbreak, I say to myself, "OK, that'll get people realizing how lucky we are to have vaccines."