When I was 20, I would have taken a bullet in the head to never have to be 35.

It’s all about control. Control is illusory. No matter what university you go to, no matter what degree you hold, if your goal is to become master of your own destiny, you have more to learn. Parkinson’s is a perfect metaphor for lack of control. Every unwanted movement in my hand or arm, every twitch that I cannot anticipate or arrest, is a reminder that even in the domain of my own being, I am not calling the shots. I tried to exert control by drinking myself to a place of indifference, which just exacerbated the sense of miserable hopelessness.

The only thing worse than an opportunity you don't deserve is blowing an opportunity.

The 'Rescue Me' gig was a unique opportunity to play a character - a misanthropic, angry guy - who was so contrary to how people think of me.

But the key to our marriage is the capacity to give each other a break. And to realize that it's not how our similarities work together; it's how our differences work together.

My age makes me think how valuable life is. How bad is something like Parkinson's in relation to not having life at all?

I saw a birthday card the other day, and it said, "If you didn't know how old you were, how old would you think you were?" I started changing it in my mind right away to, "If you didn't know how sick you were, how sick would you think you were?"