Scepticism is effortful and costly. It is better to be sceptical about matters of large consequences, and be imperfect, foolish and human in the small and the aesthetic.

If you sat with a pencil and jotted down all the decisions you've taken in the past week, or, if you could, over your lifetime, you would realize that almost all of them have had asymmetric payoff, with one side carrying a larger consequence than the other. You decide principally based on fragility, not probability. Or to rephrase, You decide principally based on fragility, not so much on True/False.

Go to parties. You can't even start to know what you may find on the envelope of serendipity. If you suffer from agoraphobia, send colleagues.

If you see fraud and do not say fraud, you are a fraud.

Anything organic requires some dose of variability so it can adapt all the time, and fixing things is not a good idea.

Aesthetics, ethics, and many good things in humans are contagious.

The more data we have, the more likely we are to drown in it.