Every audience is different, even within the same venue. You have to just make every audience your audience; you can't pre-judge an audience based on the size of the room or the type of room.
Patton OswaltWe're rewarding either the reality or the appearance of youth, which is why you have all these people in their fifties trying to act like they're seventeen. You know, it's great to be young. Be young. By all means, be young. But always remember that youth is also kinda dumb, and doesn't know a lot yet.
Patton OswaltI have a lot of friends who were stand-ups, and they just stopped after a while, because they didn't like that battle, or they just couldn't do it. And then they would get on a sitcom and get visible and get back into it, because the audience was just way easier on them. But they lost those crucial years of learning to turn any audience into your audience.
Patton OswaltIf the victories we create in our heads were let loose on reality, the world we know would drown in blazing happiness.
Patton OswaltThe apocalypse is coming, that's the one thing I like about George Bush, I really think he can get us into the ... apocalypse, like the BIBLICAL ... I really think he believes that he'll be the guy in the white hat. I think he's read the Stephen King novel The Stand a couple times, and he really thinks there's a dark man in the desert somewhere and he's gonna fight him or something.
Patton Oswalt