The art of research [is] the art of making difficult problems soluble by devising means of getting at them.

Innocent, unbiased observation is a myth.

Science is the art of the solvable.

We cannot point to a single definitive solution of any one of the problems that confront us — political, economic, social or moral, that is, having to do with the conduct of life. We are still beginners, and for that reason may hope to improve. To deride the hope of progress is the ultimate fatuity, the last word in poverty of spirit and meanness of mind. There is no need to be dismayed by the fact that we cannot yet envisage a definitive solution of our problems, a resting-place beyond which we need not try to go.

Scientists who think science consists of unprejudiced data-gathering without speculation are merely cows grazing on the pasture of knowledge.

I shall borrow two words used for a slightly different purpose by the great demographer Alfred Lotka to distinguish between the two systems of heredity enjoyed by man: endosomatic or internal heredity for the ordinary or genetical heredity we have in common with animals; and exosomatic or external heredity for the non-genetic heredity that is peculiarly our own - the heredity that is mediated through tradition, by which I mean the transfer of information through non-genetic channels from one generation to the next.

In all sensation we pick and choose, interpret, seek and impose order, and devise and test hypotheses about what we witness. Sense data are taken, not merely given: we learn to perceive.... The teacher has forgotten, and the student himself will soon forget, that what he sees conveys no information until he knows beforehand the kind of thing he is expected to see.