Pathological states are the consequence of several determinate factors acting simultaneously...The manifestations of any given agent differ profoundly from one person to another. ...Each noxious agent can express itself by a great variety of different pathological states. ...Different agents can elicit similar reactions. ...The total environment and the (interior medium) constitute a multifactorial system.
Rene DubosClearly, health and disease cannot be defined merely in terms of anatomical, physiological, or mental attributes. Their real measure is the ability of the individual to function in a manner acceptable to himself and to the group of which he is a part.
Rene Dubos