You need to figure out what the 2 or 3 most important things are, and then just do those.

Most founders have not managed people before, and they certainly haven't managed managers.

You also really want to take the time to think about how the market is going to evolve.You need a market that's going to be big in 10 years.

Remember that you are more likely to die because you execute badly than get crushed by a competitor.

I believe in fighting with investors to reduce the amount of equity they get and then being as generous as you possibly can with employees.

One of the pieces of advice that we give at YC is: try to work together on a project rather than just doing an interview.

Startups are very hard no matter what you do; you may as well go after a big opportunity.