Solving big problems is easier than solving little problems.

When I was growing up, I always knew I'd be in the top of my class in math, and that gave me a lot of self-confidence.

If you had all the world's information directly attached to your brain, or an artificial brain that was smarter than your brain, you'd be better off.

But the vast majority of books ever written are not accessible to anyone except the most tenacious researchers at premier academic libraries. Books written after 1923 quickly disappear into a literary black hole.

It's a romantic notion that you're going to have one brilliant idea and then everything is going to be great... but the execution and delivery are what's key.

If what we are doing is not seen by some people as science fiction, it's probably not transformative enough

Too few people in computer science are aware of some of the informational challenges in biology and their implications for the world. We can store an incredible amount of data very cheaply.