[With R-rated movie] you're not dealing with the restrictions imposed by the FCC. They're self-imposed. In a way, that does make it harder. You actually have to think about it, as opposed to just taking for granted that you're not going to be able to do this.
Seth MacFarlaneNobody sets out to offend or shock for the sake of shocking. You set out to get laughs.
Seth MacFarlane