Man can sin against nature in two ways. First, when he sins against his specific rational nature, acting contrary to reason. In this sense, we can say that every sin is a sin against man's nature, because it is against man's right reason.
Thomas AquinasSecondly, man sins against nature when he goes against his generic nature, that is to say, his animal nature. Now, it is evident that, in accord with natural order, the union of the sexes among animals is ordered towards conception. From this it follows that every sexual intercourse that cannot lead to conception is opposed to man's animal nature.
Thomas Aquinas