Leonardo da Vinci did not take received wisdom - whether from ancient classical thinkers or medieval scholars or from the Bible - without questioning it. And this was the beginning of the scientific method. This is another lesson for our time: that when we have evidence that contradicts a certain belief, we should be willing to change it. I think this made Leonardo, in some ways, a person who better understood the beauty of God's creation than a person who just takes all received wisdom from the Bible on faith.

Leonardo da Vinci was lucky to be born the same year that Johannes Gutenberg opened his printing shop. As a young person, he could get information about whatever struck his curiosity. The Internet is to our age what Gutenberg's press was to his, so he would have loved being alive today.

I wonder now how tough you have to be to get big things done.

The Mona Lisa, to me, is the greatest emotional painting ever done. The way the smile flickers makes it a work of both art and science, because Leonardo understood optics, and the muscles of the lips, and how light strikes the eye - all of it goes into making the Mona Lisa's smile so mysterious and elusive.

Jobs has within him sort of this conflict, but he doesn't quite see it as a conflict between being hippie-ish and anti-materialistic but wanting to sell things like Wozniak's board. Wanting to create a business.

I think the biggest innovations of the twenty-first century will be the intersection of biology and technology. A new era is beginning, just like the digital one was when I was his age.

Mainly, the reason people who didn't succeed had trouble because they had trouble forming teams. They didn't know how to collaborate.