The gym and the treadmill is a good idea. But the problem is we spend so much effort in marketing messaging, deluding people into thinking if you get on your treadmill or you go to the gym, that's what you need. People who join a gym, the vast majority of them have quit within nine months and almost all of them have quit within two years. So if it's a longevity strategy, does not work.

The brutal reality about aging is that it has only an accelerator pedal. We have yet to discover whether a brake exists for people.

If one fails to develop goals that give meaning to one’s existence, if one does not use the mind to it’s fullest, then good feelings fulfill just a fraction of the potential we possess. True happiness involves the pursuit of worthy goals. Without dreams, without risks, only a trivial semblance of living can be achieved.

A long healthy life is no accident. It begins with good genes, but it also depends on good habits.

I live on the water. I live in a neighborhood that's consummately connected to my neighbors. I bump into them every day. I can bike to work.

Exercise, from a public health perspective, is an unmitigated failure. The world's longest-lived people live in environments that nudge them into more movement. They don't use power tools, they do their own yard work, they grow a garden.

It's hard to reach [the age of] 100. We're not programmed for longevity. We are programmed for something called procreative success.