If you hear an expert talking about the Internet and saying it [does] this, or it will do that, you should treat it with the same skepticism that you might treat the comments of an economist about the economy or a weatherman about the weather.

Your genome knows much more about your medical history than you do.

People are mostly focused on defending the computers on the Internet, and there's been surprisingly little attention to defending the Internet itself as a communications medium. And I think we probably do need to pay some more attention to that, because it's actually kind of fragile.

The computers are in control. We just live in their world.

I am convinced that we humans are just at the beginning of our journey, on our way to becoming something more wonderful than we can imagine.

[Language is] really a pretty amazing invention if you think about it. Here I have a very complicated, messy, confused idea in my head. I'm sitting here making grunting sounds and hopefully constructing a similar messy, confused idea in your head that bears some analogy to it.

A novice was trying to fix a broken Lisp machine by turning the power off and on. Knight, seeing what the student was doing, spoke sternly: "You cannot fix a machine by just power-cycling it with no understanding of what is going wrong." Knight turned the machine off and on. The machine worked.