By the time I was 11, I wanted to be a comedian. So all those years later, I've managed to achieve my dream as a kid, and it wasn't easy. I'm on the [Hollywood] Walk of Fame and I'm one of the 25 most influential Hispanics in America, according to Time Magazine. I think my duty is to go back and tell kids, 'Whatever color you are, wherever you come from, anything and everything is possible.' And I'm living proof.

We need to get better at voting and be a voice for the people who do not have one.

When I first heard about Beverly Hills Chihuahua, I thought, no. This, this is ridiculous. And then you read the script and you close the script and you go, "They aren't going to be able to do that with real dogs. How are they going to do that?" You're going to see the strings. But they did.

George: Why've you had a grudge against your brother for 15 years? Benny: We Lopezes are a proud people... George: You have a birthday lunch at Denny's every month. We're not that proud!

No Angie, it's instant. Like when someone trips in the cafeteria and you're laughing so hard milk comes out of your nose, the guy next to you is laughing so hard he accidentally farts. BOOM! Friends for life!

If laughter is the best medicine, I promise to continue to make you laugh as my wife and I work together with the National Kidney Foundation to save lives.

It's good to see people not smoking. You get dressed up, and you smoke, and it gets in your clothes. You go, 'What should I wear tonight?' 'I don't know, honey, how about something menthol?'