Twitter has been my life's work in many senses. It started with a fascination with cities and how they work, and what's going on in them right now.

The strongest thing you can cultivate as an entrepreneur is to not rely on luck but cultivating an ability to recognize fortunate situations when they are occurring.

I am someone who tweets about what I have for breakfast, what I have for lunch, what I have for dinner, and for 99.99999 percent of the world, it's useless. It's meaningless. But for my mother, she loves it.

Those words are from Lynda Barry's novel 'Cruddy.' I've carried them with me for some time. There's a lot in my life I wasn't expecting. One is the realization that I stood at this pulpit and delivered a reading for my own graduation...15 years ago. Unexpectedly, I'm old.

What I love about New York is just the electricity I feel right away.

Great companies don't just have one founding moment. They have many founding moments.

'Luck' is recognizing when the situation encourages build out and execution.