The office is a romantic enabler because you're always around the person you have a crush on. There's no escape from, and maybe no desire to escape from, those pressure-cooker conditions. And there's an automatic series of things you have to talk about all the time.

The whole time I was writing, I had to fight my normal inclination to be funny, to sort of patch humor in, in order to convey all of the disruptions of the disease to the family dynamic, the loss of individuality, the impact on professional life, and the sanity of the main character. Of course, that's not to say it never sneaks in; there's some black comedy in there, like when he shows up to court wearing a bicycle helmet and won't take it off.

We had the great good fortune and shortcomings of character that marked every generation that had never seen war.

I'm being provided with some emotional ballast by giving me an intimate portrait of one character in particular in contrast to the collective. I'm fortunate that I had very sympathetic readers, but ordinarily - if a book makes you laugh too much, it shifts from "literature" to "entertainment."

I think a fairly common behavior among fiction writers is that they want to help. They're generally charitable people. They're interested in the world. They're curious, they're empathetic. They understand suffering. They don't turn away from that. But what they do is essentially useless. Except for the sake of the thing itself.

Yet for all the depression no one ever quit. When someone quit, we couldn't believe it. 'I'm becoming a rafting instructor on the Colorado River,' they said. 'I'm touring college towns with my garage band.' We were dumbfounded. It was like they were from another planet. Where had they found the derring-do? What would they do about car payments? We got together for going away drinks on their final day and tried to hide our envy while reminding ourselves that we still had the freedom and luxury to shop indiscriminately.

Everything was always something but something – and here was the rub – could never be everything.