Part of the fun of being alive is knowing that you're annoying the hell out of someone else.

I may be biting off more than I can chew, but with 'The Simpsons' and with 'Futurama,' what I'm trying to do in the guise of light entertainment, if this is possible - is nudge people, jostle them a little, wake them up to some of the ways in which we're being manipulated and exploited.

I think people who work in comedy and humor are hesitant to analyze it too much, because you feel like if you take it apart, you'll break it and not be able to put it back together again.

The entire world of grown-ups is corrupt and stupid.

Masturbation is nothing to be ashamed of. It's nothing to be particularly proud of, either.

My father was a really sharp cartoonist and filmmaker. He used to tape-record the family surreptitiously, either while we were driving around or at dinner, and in 1963 he and I made up a story about a brother and a sister, Lisa and Matt, having an adventure out in the woods with animals.

I basically drew my own family. My father's name is Homer. My mother's name is Margaret. I have a sister Lisa and another sister Maggie, so I drew all of them. I was going to name the main character Matt, but I didn't think it would go over well in a pitch meeting, so I changed the name to Bart.