I don't drink a lot. My family calls me an old soul. And my friends call me a pussy.

I like 'Donnie Darko;' it's a cool take on dreams and sleep.

My friends drink everywhere. They even drink at the laundromat. I tried drinking at the laundromat, and I thought I was in a submarine, navigating the Sea of White Panties with my Spanish-speaking crew. I was like, "Mrs. Sanchez, set the coordinates to Permanent Press! Give me some quarters and another drink! This place is starting to look like a laundromat."

I try to think up material that might apply to the subjects they are studying. How many mitochondria does it take to power a cell? One. Because mitochondria are the powerhouse of the cell. Not ready for prime time, that one.

I think sometimes you don't understand how to convey an idea, depending on the moment you're living in.

In my twenties, I thought it was getting a sitcom. Then I got a sitcom pilot in my early thirties, and realized I didn't want it. It was a rude awakening. When it wasn't picked up, I was crushed, but then in retrospect I've made two films and produced three one-man shows since then. It's the luckiest thing that happened in my life.

I find my fans are really funny people. Most comedians can't say that about their fans.