It is a common failing-and one that I have myself suffered from-to fall in love with a hypothesis and to be unwilling to take no for an answer. A love affair with a pet hypothesis can waste years of precious time. There is very often no finally decisive yes, though quite often there can be a decisive no.
Peter MedawarTo abdicate from the rule of reason and substitute for it an authentication of belief by the intentness and degree of conviction with which we hold it can be perilous and destructive. Religious beliefs give a spurious spiritual dimension to tribal enmities.
Peter MedawarNo scientist is admired for failing in the attempt to solve problems that lie beyond his competence. ... Good scientists study the most important problems they think they can solve. It is, after all, their professional business to solve problems, not merely to grapple with them.
Peter Medawar