Evolution isn't over. We are the experience that the universe is having.
Understanding why something happened does not help to reduce the problem.
Optimism, that is healthy in its application, will inevitably result in better physical and emotional health.
Memories are like holograms: you recreate in your head the whole image of something which isn't there.
Disappointment requires adequate planning.
The fact is that there is nothing wrong with most of us that a good, clean change of attitude and some new skills wouldn't fix.