Because so few people make an actual long term commitment to what they're building, the ones that do have a huge advantage.

The natural state of a start-up is to die; most start-ups require multiple miracles in their early days to escape this fate.

Long term thinking is so rare anywhere, but especially in startups. This is a huge advantage if you do it.

You never want to be in a place where an employee has vested 3 out of the 4 years of stock and they start thinking about leaving.

A third advantage of mission oriented companies, is that people outside the company are more willing to help you.

The startups that do well are the ones that are working all the time.

It's difficult to get large groups of people, to the extreme levels of focus and productivity that you need, for a startup to be successful.