Move fast. Speed is one of your main advantages over large companies.

You also really want to take the time to think about how the market is going to evolve.You need a market that's going to be big in 10 years.

You don't need to make the structure complicated, in fact you shouldn't. All you need is for every employee to know who their manager is.

If you ever take your foot off the gas pedal, things will spiral out of control, snowball downwards.

For most of the early hires you make in a startup, experience doesn't matter very much, and you should go for aptitude.

One thing that often disrupts momentum and really shouldn't is competitors.

If you don't need it yourself, and you're building something that someone else needs, realize you're at a big disadvantage.