Most startups are not nearly focussed enough. They work hard...maybe, but they don't work hard on the right things.

Facebook has this famous poster that says move fast and break things. But at the same time they manage to be obsessed with quality.

You're saying no ninety-seven times out of a hundred, and most founders find they have to make a very conscious effort to do this.

Every first time founder waits too long, everyone hopes that an employee will turn around. But the right answer is to fire fast.

You also want people who are maniacally determined and that is slightly different than having a risk tolerant attitude.

A third advantage of mission oriented companies, is that people outside the company are more willing to help you.

In the early stage of a startup, hiring senior people is usually a mistake. You just want people that get stuff done.